Efficacy and Safety of Antifungal Additives in Optisol-GS Corneal Storage Medium

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Efficacy and safety of antifungal additives in Optisol-GS corneal storage medium.

IMPORTANCE Optisol-GS, the most common corneal storage medium in the United States, contains antibacterial but no antifungal supplementation. Most postkeratoplasty endophthalmitis and keratitis cases are now of a fungal origin. OBJECTIVE To assess the efficacy and safety of voriconazole and amphotericin B in reducing Candida species contamination of Optisol-GS under normal storage conditions....

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Corneal temperature reversal after storage in Chen medium compared with Optisol GS.

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A randomized, double-masked clinical trial of Optisol-GS vs Chen Medium for human corneal storage.

OBJECTIVE To determine whether the clinical outcome of corneal transplantation performed with tissue stored in Chen Medium (CM; Chen Laboratories, Phoenix, Md) is superior to that of Optisol-GS (Chiron Ophthalmics, Irvine, Calif). DESIGN Randomized, double-masked trial. PARTICIPANTS AND SETTING Ninety patients undergoing corneal transplantation at a tertiary center. INTERVENTION Donor cor...

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Effects of organ culture and Optisol-GS storage on structural integrity, phenotypes, and apoptosis in cultured corneal epithelium.

PURPOSE A previous report has described the use of eye bank storage of cultured human limbal epithelial cells (HLECs) to provide a reliable source of tissue for treating limbal stem cell deficiency. In the present study, conventional organ culture (OC) storage and Optisol-GS (Bausch & Lomb, Irvine, CA) storage of cultured HLECs were compared. METHODS Three-week HLEC cultures were either organ...

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comparison of donor cornea storage in optisol-gs and the central eye bank of iran (cebi) medium

purpose: optisol-gs is still the most popular cold storage medium used in the united states for short term preservation of donated corneas. cebi medium is a new cold storage medium made by the central eye bank of iran for donor cornea storage. this study was conducted to compare the quantitative and qualitative indices of the donated corneas maintained in optisol-gs versus in the cebi medium. m...

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ژورنال

عنوان ژورنال: JAMA Ophthalmology

سال: 2014

ISSN: 2168-6165

DOI: 10.1001/jamaophthalmol.2014.397